It's Fascinating Friday! Did you know? Colostrum, also known as "mother's gold" plays an important role in immunity. Newborn puppies who have received adequate colostrum from their mothers don't respond to vaccines because mom’s maternal antibodies interfere. This is why puppies are vaccinated every 3 to 4 weeks until 16 weeks of age. Eventually, at some point during this timeframe one or more vaccines will “take," explains veterinarian Dr. Ken Tudor.